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A Guide to Probiotics

Your Gut’s Protective Ally

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FROM THE NATURE

What are Probiotics?

Probiotics, known as "good" or "friendly" bacteria, are microorganisms naturally found within our bodies. When present in sufficient quantities, they offer numerous benefits for overall health, particularly for the digestive system1. Probiotics play a crucial role in maintaining and restoring the balance of gut microbiota, which can be easily disrupted1. They effectively support long-term gastrointestinal health2,3,4, and help prevent complications associated with Antibiotic-Associated Dysbiosis5.

Types of Probiotics6

Bacteria-based probiotics

  • Bifidobacterium
  • Lactobacillus

Yeast-based probiotic

  • Saccharomyces boulardii

INSIDE YOUR BODY

Get to Know Your Gut Microbiota

The gut microbiota is a vast community of bacteria, fungi, and other microorganisms that live within your gut7, playing a vital role in maintaining your health. Think of them as trillions of tiny helpers working tirelessly behind the scenes to ensure your body functions smoothly and stays in good health.

However, the balance can easily be disrupted by many factors like8,9:

  • Viruses
  • Antibiotics Intake
  • Chronic Diseases
  • Stress
  • Brutal Change of Diet
When your gut microbiota becomes imbalanced or unhealthy, it can have a significant impact on your overall well-being10, leading to various health conditions.
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Reference:

  1. Hill C, Guarner F, Reid G, et al. Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol. 2014 Aug;11(8):506-14. doi: 10.1038/nrgastro.2014.66. Epub 2014 Jun 10. PMID: 24912386.
  2. BIOCODEX. Saccharomyces boulardii CNCM I-745® - Company Core Data Sheet. 2021. Reference: I.2963/EN.
  3. McFarland, LV. Systematic review and meta-analysis of Saccharomyces boulardii in adult patients. World journal of gastroenterology: WJG. 2010; 16(18): 2202.
  4. Kabbani et al. Prospective randomized controlled study on the effects of Saccharomyces boulardii CNCM I-745 and amoxicillin-clavulanate or the combination on the gut microbiota of healthy volunteers. Gut Microbes. 2017 Jan 2;8(1):17-32. doi: 10.1080/19490976.2016.1267890.
  5. Probiotics Database, Optibac Probiotocs, www.optibacprobiotics.com/professionals/probiotics-database
  6. Chen Y, Zhou J, Wang L. Role and Mechanism of Gut Microbiota in Human Disease. Front Cell Infect Microbiol. 2021;11:625913. Published 2021 Mar 17. doi:10.3389/fcimb.2021.625913
  7. Weiss GA, Hennet T. Mechanisms and consequences of intestinal dysbiosis. Cell Mol Life Sci. 2017 Aug;74(16):2959- 2977. doi: 10.1007/s00018-017-2509-x
  8. Hrncir T. Gut Microbiota Dysbiosis: Microorganisms. 2022 Mar 7;10(3):578. doi: 10.3390/microorganisms10030578
  9. Queen J, Zhang J, Sears CL. Oral antibiotic use and chronic disease: Gut Microbes. 2020;11(4):1092-1103. doi:10.1080/19490976.2019.1706425
  10. WebMD. (n.d.). What Is Dysbiosis? Retrieved November 2023, from https://www.webmd.com/digestive-disorders/what-is-dysbiosis#1-4
  11. Miller SA, Wu RKS, Oremus M. Obes Rev. 2018;19(11):1463-1475. doi:10.1111/obr.12717
  12. Hirsch AG, Pollak J, Glass TA, et al. Early-life antibiotic use Clin Exp Allergy. 2017;47(2):236-244. doi:10.1111/cea.12807


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